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'Researchers propose an intervention that works scientifically and clinicians prescribe what is scientifically proven to be best. However, the best interventions can be affected by health financing issues. The Editor’s pick this month is a health-economics paper. Sun Kuie Tay and fellow researchers from Singapore have conducted a study which demonstrates that school-based quadrivalent HPV vaccination is a cost-effective intervention with clinical benefits. This paper highlights the importance of a multidisciplinary approach in making the case for useful health interventions.'