New treatment recommendations for pregnant women with HIV

A group of international experts have issued new recommendations on antiretroviral drugs for pregnant women living with HIV that could help them make more informed choices.

Published in the BMJ, the recommendations are different from current guidelines. The authors say they are intended to support shared decision-making between pregnant women and healthcare providers.

Recent trial evidence has suggested that the most commonly used drug combinations to treat HIV in pregnant women may increase the risk of premature birth and neonatal death compared with other drug combinations.

Evidence from the experts’ two systematic reviews led the panel to recommend older alternatives instead of the most widely used drug combinations to help reduce the risk of premature birth and neonatal death.

The panel acknowledge that the number of antiretroviral therapy options that women can choose from and can be prescribed varies considerably throughout the world - and that, in many settings, alternative drugs may not be available.ADNFCR-2094-ID-801839790-ADNFCR