Oncology

FDA approves ovarian cancer drug

The US Food and Drug Administration (FDA) has approved a new drug to treat ovarian cancer. It is called Rubraca and has been approved for women with advanced ovarian cancer who have already had two or more rounds of chemotherapy and whose tumours have a specific mutation - deleterious BRCA - as...

Scientists reveal how breast cancer spreads before a tumour develops

Even before tumours develop, breast cancer cells with a few defined molecular alterations can spread to organs, remain quiet for long periods of time, and then awaken to form aggressive, deadly breast cancer metastasis. This is according to a team of investigators led by researchers at Icahn School...

Biomarkers of response to breast cancer treatment identified

A new study could provide insight into why some breast cancers respond to treatment whilst others resist. Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center, US, have reported that they have identified biomarkers that could be used to predict how patients with...

Scientists develop tool to aid breast cancer surgery

Researchers have developed an optical fibre probe that distinguishes breast cancer tissue from normal tissue. It is hoped that this could allow surgeons to be much more precise when removing breast cancer. Scientists at the University of Adelaide, Australia, said the device could help prevent...

UK’s Nice urges doctors to offer breast cancer prevention drug

The UK’s National Health Service (NHS) watchdog has issued new guidelines that recommend healthy women be prescribed cheap drugs that will cut the risk of developing breast cancer by half. According to the National Institute for Health and Care Excellence (Nice), clinicians should consider...

Scientists create new drug design to improve breast cancer treatment

A new study by scientists from the Florida campus of The Scripps Research Institute (TSRI), US, has offered a novel structure-based drug design strategy aimed at improving breast cancer treatment. Resistance to breast cancer therapies remains a significant problem, whilst side effects, including an...

UK launches personalised breast cancer programme

The Cancer Research UK (CRUK) Cambridge Institute has launched a personalised breast cancer programme to map patients' DNA and RNA to tailor treatment for individuals. According to CRUK, the project will analyse the genome and all expressed genes of tumour cells from 250 breast cancer patients...

Vitamin D linked to breast cancer outcome

Women with higher vitamin D levels in their blood following a breast cancer diagnosis had significantly better long-term outcomes, according to new research from Kaiser Permanente and Roswell Park Cancer Institute, US. Vitamin D deficiency has been associated with the risk for several cancers. It...

Women warned over non-lump breast cancers

Women are being warned that a lump is not the only sign of breast cancer and that they should be aware of the other symptoms of the disease. Researchers from UK universities, including University College London (UCL), the University of Exeter and the University of Durham, found that although most...

GPs ‘have low awareness of tamoxifen as breast cancer prevention’

New research presented at the National Cancer Research Institute’s (NCRI) Conference has shown that there is a low awareness among GPs of tamoxifen as a preventive treatment for women at medium or high risk of breast cancer. The study - led by Professor Jack Cuzick at Queen Mary, University...