Sperm could be used to deliver targeted cancer treatment

Doctors are looking at the drug delivery opportunities that could be provided by human sperm. Researchers from the Institute for Integrative Nanosciences in Germany have started researching the possibility of using sperm to deliver medication to female cancer patients. 

The team found that sperm submerged in an active ingredient that is used in cancer drugs can absorb large doses of it. The sperm can then be collected into microscopic mechanical harnesses, which contain iron.

Doctors can use the iron to direct the sperm in the direction of the tumour using external magnetic fields, so they can deliver a high dose of the medication. Once the sperm is in place, the idea is for the harness to release the sperm, which will then burrow into the tumour tissue, exposing more cancer cells to the treatment.

It is hoped that this will allow for more direct treatment of cancerous tumours than any other currently available option. 

Experimenting with bull sperm, which is similar in size to human sperm, the researchers found that cancerous cells were reduced by 87 per cent in 72 hours, which is far more effective than treating with traditional forms of drug delivery. 

The findings could help hundreds of thousands of women who are diagnosed with gynaecological cancers and other female reproductive tract diseases. ADNFCR-2094-ID-801834868-ADNFCR