Oncology

New hope for ovarian cancer patients, as scientists repurpose inhibitors

Repurposing HDAC inhibitors could be a therapeutic option for patients suffering from ovarian cancer, a new study has found. The inhibitors have already been approved by the FDA for the treatment of other diseases, such as leukaemia, but have not been used for ovarian cancer until now. Researchers...

Breakthrough in identifying second breast cancer risk for women with BRCA mutation

Women with high-risk BRCA gene mutations can now have their chances of a second breast cancer identified with greater accuracy. By testing for a number of other genetic variants that all carry a small impact on the risk of breast cancer can help to form a fuller picture. That is according to...

Combination breast cancer treatment targets tumour growth

Combining a cancer therapy, which activates a defective protein and is currently undergoing clinical trial, with a second drug therapy that helps suppress tumour blood vessels found in cancer cells, can help to significantly reduce the spread of breast cancer tumours while also causing cancer cell...

Scientists discover 110 genes linked to breast cancer

A new study has linked 110 genes to an increased risk of breast cancer, paving the way for a better understanding of the disease. Scientists at The Institute of Cancer Research, London in the United Kingdom have analysed maps of DNA regions using a pioneering genetic technique. This has enabled...

Aggressive breast cancer tumours 'can be made vulnerable'

Breast cancer patients with aggressive tumours could be able to undergo less intensive treatments in the future, thanks to a new discovery. Scientists at Lund University have successfully developed a means of disrupting tumour cells' communication with the surrounding cells, and thereby making...

Increase in tissue stiffness 'could lead to greater breast cancer risk'

New research has highlighted a potential link between the stiffness of tissues surrounding cancer cells and the aggressiveness with which breast cancer is able to develop. Doctoral candidate at the Stevens Institute of Technology, US, Deep Parikh, will be presenting his research at this year's...

Study shows varying results for breast cancer recurrence tests

Branded tests used to determine the likelihood of breast cancers returning after treatment vary in accuracy, recent research has shown. A study conducted by Queen Mary University of London, UK, funded by Cancer Research UK and published in the JAMA Oncology journal, evaluated four tests on tumour...

Fathers’ gene mutation could be raising daughters’ ovarian cancer risk

A new gene mutation discovered by US scientists could mean that fathers may be increasing the risk of ovarian cancer for their daughters. The gene - inherited through the X-chromosome, one of which is passed on by men to their daughters - is independent of other known susceptibility genes that...

Soft chemotherapy ‘effective in older breast cancer patients’

A combination of ‘soft’ chemotherapy with antiHER2 therapy has been found to be highly active and present low toxicity for older patients with HER2 positive metastatic breast cancer. According to the scientists who made the discovery, this is important in a frail population. Professor...

Mother’s breast cancer type may affect newborn health status

For breast cancer survivors, the risk of giving birth prematurely may depend on the type of breast cancer they had. This is according to a new study from the University of North Carolina Lineberger Comprehensive Cancer Center, US. The researchers analysed health indicators for children born to...